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Qué (quién) es vincristine - definición

CHEMICAL COMPOUND

Vincristine sulfate; Oncovin; C46H56N4O10; ATC code L01CA02; ATCvet code QL01CA02; Marqibo; Onco TCS; Vincasar; Vincasar PFS; Vincrex; Vinkristin; Marqibo Kit

vincristine

[v?n'kr?sti:n]

¦ noun Medicine a compound obtained from a species of periwinkle (plant) and used to treat acute leukaemia and other cancers.

Origin

1960s: from mod. L. Vinca (see vinca) + a second element perh. based on crista + -ine⁴.

MOPP (chemotherapy)

CHEMOTHERAPY REGIMEN

MOPP regimen; Mustargen Oncovin Procarbazine Prednisone; MOPP (medicine)

MOPP is a combination chemotherapy regimen used to treat Hodgkin lymphoma. The acronym is derived from the component drugs of the regimen:

https://en.wikipedia.org/wiki/MOPP_(chemotherapy)

Chemotherapy regimen

MULTI-DRUG TREATMENTS FOR CANCER

Induction regimens; Chemotherapy protocol; Antineoplastic protocols; Antineoplastic combined chemotherapy protocols; VAPEC-B; ChlVPP/EVA; M-BACOD; MACOP-B; ProMACE-MOPP; ProMACE-CytaBOM; Thal/Dex; EE4A; EE-4A; Vincristine/actinomycin; Regimen I; DD-4A; List of chemotherapy regimens; CTD (chemotherapy); Chemo regimen; Chemo regimens; DAM (chemotherapy); Chemotherapy regimens; R-benda; GDP (chemotherapy); V-DCEP

A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations. In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy.

https://en.wikipedia.org/wiki/Chemotherapy_regimen

Wikipedia

Vincristine

Vincristine, also known as leurocristine and marketed under the brand name Oncovin among others, is a chemotherapy medication used to treat a number of types of cancer. This includes acute lymphocytic leukemia, acute myeloid leukemia, Hodgkin's disease, neuroblastoma, and small cell lung cancer among others. It is given intravenously.

Most people experience some side effects from vincristine treatment. Commonly it causes a change in sensation, hair loss, constipation, difficulty walking, and headaches. Serious side effects may include neuropathic pain, lung damage, or low white blood cells which increases the risk of infection. Use during pregnancy may result in birth defects. It works by stopping cells from dividing properly. It is vital that it not be given intrathecally, as this may kill.

Vincristine was first isolated in 1961. It is on the World Health Organization's List of Essential Medicines. It is a vinca alkaloid that can be obtained from the Madagascar periwinkle Catharanthus roseus.

https://en.wikipedia.org/wiki/Vincristine

Ejemplos de uso de vincristine

1. "That month, Leah Beth had the first of her fortnightly doses of two chemotherapy drugs, Vincristine and Actinomycin.

2. Wayne, 18, was on the verge of beating leukaemia when Syrian–born Dr Feda Mulhem failed to make basic checks and told a junior to inject Vincristine.

3. The CMO issued a warning to NHS trusts in November 2001 that patients could die if the wrong drug was injected into the spine, particularly vincristine, which is commonly given intravenously as part of the same course of treatment.